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Highly Hydrophilic and Lipophilic Derivatives of Bile Salts

Lipophilicity of 15 derivatives of sodium cholate, defined by the octan-1-ol/water partition coefficient (log P), has been theoretically determined by the Virtual log P method. These derivatives bear highly hydrophobic or highly hydrophilic substituents at the C3 position of the steroid nucleus, bei...

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Detalles Bibliográficos
Autores principales: Vázquez-Tato, M. Pilar, Seijas, Julio A., Meijide, Francisco, Fraga, Francisco, de Frutos, Santiago, Miragaya, Javier, Trillo, Juan Ventura, Jover, Aida, Soto, Victor H., Vázquez Tato, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268814/
https://www.ncbi.nlm.nih.gov/pubmed/34206572
http://dx.doi.org/10.3390/ijms22136684