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Ineffective Erythropoiesis in β-Thalassaemia: Key Steps and Therapeutic Options by Drugs

β-thalassaemia is a rare genetic condition caused by mutations in the β-globin gene that result in severe iron-loading anaemia, maintained by a detrimental state of ineffective erythropoiesis (IE). The role of multiple mechanisms involved in the pathophysiology of the disease has been recently unrav...

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Detalles Bibliográficos
Autores principales: Longo, Filomena, Piolatto, Andrea, Ferrero, Giovanni Battista, Piga, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268821/
https://www.ncbi.nlm.nih.gov/pubmed/34281283
http://dx.doi.org/10.3390/ijms22137229