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Ineffective Erythropoiesis in β-Thalassaemia: Key Steps and Therapeutic Options by Drugs
β-thalassaemia is a rare genetic condition caused by mutations in the β-globin gene that result in severe iron-loading anaemia, maintained by a detrimental state of ineffective erythropoiesis (IE). The role of multiple mechanisms involved in the pathophysiology of the disease has been recently unrav...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268821/ https://www.ncbi.nlm.nih.gov/pubmed/34281283 http://dx.doi.org/10.3390/ijms22137229 |