A pH-Sensitive Polymeric Micellar System Based on Chitosan Derivative for Efficient Delivery of Paclitaxel

In this study, an amphiphilic conjugate based on mPEG and cholesterol-modified chitosan with hydrazone bonds in the molecules (mPEG-CS-Hz-CH) was successfully synthesized. Using the polymer as the carrier, the paclitaxel (PTX)-loaded mPEG-CS-Hz-CH micelles were prepared by an ultrasonic probe method...

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Detalles Bibliográficos
Autores principales: Han, Yang, Pan, Jieyi, Liang, Na, Gong, Xianfeng, Sun, Shaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268857/
https://www.ncbi.nlm.nih.gov/pubmed/34206347
http://dx.doi.org/10.3390/ijms22136659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268857/
https://www.ncbi.nlm.nih.gov/pubmed/34206347
http://dx.doi.org/10.3390/ijms22136659

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