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MHC Class I Deficiency in Solid Tumors and Therapeutic Strategies to Overcome It

It is now well accepted that the immune system can control cancer growth. However, tumors escape immune-mediated control through multiple mechanisms and the downregulation or loss of major histocompatibility class (MHC)-I molecules is a common immune escape mechanism in many cancers. MHC-I molecules...

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Detalles Bibliográficos
Autores principales: Shklovskaya, Elena, Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268865/
https://www.ncbi.nlm.nih.gov/pubmed/34201655
http://dx.doi.org/10.3390/ijms22136741