An Algorithm Combining Patient Performance Status, Second Hit Analysis, PROVEAN and Dann Prediction Tools Could Foretell Sensitization to PARP Inhibitors in Digestive, Skin, Ovarian and Breast Cancers

SIMPLE SUMMARY: PARP inhibitors, a family of targeted cancer therapeutics, have been shown to be efficient in patients with some deficiencies in the homologous recombination machinery. However, a quick and reliable identification of patients who would benefit from such therapies remains a challenge....

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Detalles Bibliográficos
Autores principales: Chevrier, Sandy, Richard, Corentin, Collot, Thomas, Mananet, Hugo, Arnould, Laurent, Boidot, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268870/
https://www.ncbi.nlm.nih.gov/pubmed/34206535
http://dx.doi.org/10.3390/cancers13133113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268870/
https://www.ncbi.nlm.nih.gov/pubmed/34206535
http://dx.doi.org/10.3390/cancers13133113

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