Cargando…

Mismatch Repair Deficiency as a Predictive and Prognostic Biomarker in Molecularly Classified Endometrial Carcinoma

SIMPLE SUMMARY: We studied mismatch repair (MMR) deficiency as a predictive and prognostic biomarker in endometrial carcinoma. MMR deficiency was associated with poor outcome only when p53 aberrant and polymerase-ϵ mutant tumors were excluded from the MMR proficient subgroup, in accordance with mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Loukovaara, Mikko, Pasanen, Annukka, Bützow, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268938/
https://www.ncbi.nlm.nih.gov/pubmed/34206702
http://dx.doi.org/10.3390/cancers13133124