Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α

Age-related macular degeneration (AMD), the main cause of vision loss in the elderly, is associated with oxidation in the retina cells promoting telomere attrition. Activation of telomerase was reported to improve macular functions in AMD patients. The catalytic subunit of human telomerase (hTERT) m...

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Detalles Bibliográficos
Autores principales: Blasiak, Janusz, Szczepanska, Joanna, Fila, Michal, Pawlowska, Elzbieta, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268995/
https://www.ncbi.nlm.nih.gov/pubmed/34281248
http://dx.doi.org/10.3390/ijms22137194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268995/
https://www.ncbi.nlm.nih.gov/pubmed/34281248
http://dx.doi.org/10.3390/ijms22137194

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