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Activation of DNA Damage Tolerance Pathways May Improve Immunotherapy of Mesothelioma

SIMPLE SUMMARY: A critical step in the success of immunotherapy is the presentation of tumor-derived peptides by the major histocompatibility complex I (MHC-I) of tumor cells. These neoantigens are potentially immunogenic and trigger immune responses orchestrated by cytotoxic cells. In malignant mes...

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Detalles Bibliográficos
Autores principales: Brossel, Hélène, Fontaine, Alexis, Hoyos, Clotilde, Jamakhani, Majeed, Willems, Mégane, Hamaidia, Malik, Willems, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269013/
https://www.ncbi.nlm.nih.gov/pubmed/34199066
http://dx.doi.org/10.3390/cancers13133211