A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu(2+)-Mediated Aβ Aggregation

Copper (Cu) has been implicated in the progression of Alzheimer’s disease (AD), and aggregation of Cu and amyloid β peptide (Aβ) are considered key pathological features of AD. Metal chelators are considered to be potential therapeutic agents for AD because of their capacity to reduce metal ion-indu...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Zhang, Xiancheng, Zhong, Manli, Zhao, Pu, Guo, Chuang, Li, You, Xu, He, Wang, Tao, Gao, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269028/
https://www.ncbi.nlm.nih.gov/pubmed/34202166
http://dx.doi.org/10.3390/ijms22136842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269028/
https://www.ncbi.nlm.nih.gov/pubmed/34202166
http://dx.doi.org/10.3390/ijms22136842

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