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A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu(2+)-Mediated Aβ Aggregation
Copper (Cu) has been implicated in the progression of Alzheimer’s disease (AD), and aggregation of Cu and amyloid β peptide (Aβ) are considered key pathological features of AD. Metal chelators are considered to be potential therapeutic agents for AD because of their capacity to reduce metal ion-indu...
Autores principales: | Zhang, Xiaoyu, Zhang, Xiancheng, Zhong, Manli, Zhao, Pu, Guo, Chuang, Li, You, Xu, He, Wang, Tao, Gao, Huiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269028/ https://www.ncbi.nlm.nih.gov/pubmed/34202166 http://dx.doi.org/10.3390/ijms22136842 |
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