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Cytotoxic Activity against A549 Human Lung Cancer Cells and ADMET Analysis of New Pyrazole Derivatives

Two new pyrazole derivatives, namely compound 1 and compound 2, have been synthesized, and their biological activity has been evaluated. Monocrystals of the obtained compounds were thoroughly investigated using single-crystal X-ray diffraction analysis, FTIR spectroscopy, and NMR spectroscopy. The r...

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Detalles Bibliográficos
Autores principales: Czylkowska, Agnieszka, Szczesio, Małgorzata, Raducka, Anita, Rogalewicz, Bartłomiej, Kręcisz, Paweł, Czarnecka, Kamila, Szymański, Paweł, Pitucha, Monika, Pawlak, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269030/
https://www.ncbi.nlm.nih.gov/pubmed/34206582
http://dx.doi.org/10.3390/ijms22136692