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Discovery of Spatial Peptide Signatures for Neuroblastoma Risk Assessment by MALDI Mass Spectrometry Imaging

SIMPLE SUMMARY: The childhood tumor, neuroblastoma, has a broad clinical presentation. Risk assessment at diagnosis is particularly difficult in molecularly heterogeneous high-risk cases. Here we investigate the potential of imaging mass spectrometry to directly detect intratumor heterogeneity on th...

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Detalles Bibliográficos
Autores principales: Wu, Zhiyang, Hundsdoerfer, Patrick, Schulte, Johannes H., Astrahantseff, Kathy, Boral, Senguel, Schmelz, Karin, Eggert, Angelika, Klein, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269054/
https://www.ncbi.nlm.nih.gov/pubmed/34202325
http://dx.doi.org/10.3390/cancers13133184