Amino Acid-Mediated Intracellular Ca(2+) Rise Modulates mTORC1 by Regulating the TSC2-Rheb Axis through Ca(2+)/Calmodulin

Mechanistic target of rapamycin complex 1 (mTORC1) is a master growth regulator by controlling protein synthesis and autophagy in response to environmental cues. Amino acids, especially leucine and arginine, are known to be important activators of mTORC1 and to promote lysosomal translocation of mTO...

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Detalles Bibliográficos
Autores principales: Amemiya, Yuna, Nakamura, Nao, Ikeda, Nao, Sugiyama, Risa, Ishii, Chiaki, Maki, Masatoshi, Shibata, Hideki, Takahara, Terunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269083/
https://www.ncbi.nlm.nih.gov/pubmed/34198993
http://dx.doi.org/10.3390/ijms22136897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269083/
https://www.ncbi.nlm.nih.gov/pubmed/34198993
http://dx.doi.org/10.3390/ijms22136897

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