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Prognostic Significance of CXCR4 in Colorectal Cancer: An Updated Meta-Analysis and Critical Appraisal

SIMPLE SUMMARY: C-X-C chemokine receptor type 4 (CXCR4), a G-protein-coupled receptor, has been demonstrated to stimulate proliferation and invasiveness of many different tumors, including colorectal cancer. Through in vitro evidence, overexpression of CXCR4 has been identified as a negative prognos...

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Detalles Bibliográficos
Autores principales: Ottaiano, Alessandro, Santorsola, Mariachiara, Del Prete, Paola, Perri, Francesco, Scala, Stefania, Caraglia, Michele, Nasti, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269109/
https://www.ncbi.nlm.nih.gov/pubmed/34209026
http://dx.doi.org/10.3390/cancers13133284