Treatment with the Bacterial Toxin CNF1 Selectively Rescues Cognitive and Brain Mitochondrial Deficits in a Female Mouse Model of Rett Syndrome Carrying a MeCP2-Null Mutation

Rett syndrome (RTT) is a rare neurological disorder caused by mutations in the X-linked MECP2 gene and a major cause of intellectual disability in females. No cure exists for RTT. We previously reported that the behavioural phenotype and brain mitochondria dysfunction are widely rescued by a single...

Descripción completa

Detalles Bibliográficos
Autores principales: Urbinati, Chiara, Cosentino, Livia, Germinario, Elena Angela Pia, Valenti, Daniela, Vigli, Daniele, Ricceri, Laura, Laviola, Giovanni, Fiorentini, Carla, Vacca, Rosa Anna, Fabbri, Alessia, De Filippis, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269120/
https://www.ncbi.nlm.nih.gov/pubmed/34201747
http://dx.doi.org/10.3390/ijms22136739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269120/
https://www.ncbi.nlm.nih.gov/pubmed/34201747
http://dx.doi.org/10.3390/ijms22136739

Ejemplares similares