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Structural Characterization of EnpA D,L-Endopeptidase from Enterococcus faecalis Prophage Provides Insights into Substrate Specificity of M23 Peptidases

The best-characterized members of the M23 family are glycyl-glycine hydrolases, such as lysostaphin (Lss) from Staphylococcus simulans or LytM from Staphylococcus aureus. Recently, enzymes with broad specificities were reported, such as EnpA(CD) from Enterococcus faecalis, that cleaves D,L peptide b...

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Detalles Bibliográficos
Autores principales: Małecki, Piotr Henryk, Mitkowski, Paweł, Jagielska, Elżbieta, Trochimiak, Karolina, Mesnage, Stéphane, Sabała, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269130/
https://www.ncbi.nlm.nih.gov/pubmed/34281200
http://dx.doi.org/10.3390/ijms22137136