Multiphoton Imaging of Ca(2+) Instability in Acute Myocardial Slices from a RyR2(R2474S) Murine Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a familial stress-induced arrhythmia syndrome, mostly caused by mutations in Ryanodine receptor 2 (RyR2), the sarcoplasmic reticulum (SR) Ca(2+) release channel in cardiomyocytes. Pathogenetic mutations lead to gain of function in the c...

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Detalles Bibliográficos
Autores principales: Borile, Giulia, Zaglia, Tania, E. Lehnart, Stephan, Mongillo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269190/
https://www.ncbi.nlm.nih.gov/pubmed/34206855
http://dx.doi.org/10.3390/jcm10132821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269190/
https://www.ncbi.nlm.nih.gov/pubmed/34206855
http://dx.doi.org/10.3390/jcm10132821

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