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Multiphoton Imaging of Ca(2+) Instability in Acute Myocardial Slices from a RyR2(R2474S) Murine Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a familial stress-induced arrhythmia syndrome, mostly caused by mutations in Ryanodine receptor 2 (RyR2), the sarcoplasmic reticulum (SR) Ca(2+) release channel in cardiomyocytes. Pathogenetic mutations lead to gain of function in the c...

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Detalles Bibliográficos
Autores principales:	Borile, Giulia, Zaglia, Tania, E. Lehnart, Stephan, Mongillo, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269190/ https://www.ncbi.nlm.nih.gov/pubmed/34206855 http://dx.doi.org/10.3390/jcm10132821

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