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Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes

Halogenases create diverse natural products by utilizing halide ions and are of great interest in the synthesis of potential pharmaceuticals and agrochemicals. An increasing number of halogenases discovered in microorganisms are annotated as flavin-dependent halogenases (FDHs), but their chemical re...

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Detalles Bibliográficos
Autores principales: Jeon, Jehyun, Lee, Jaehee, Jung, Se-Min, Shin, Jae Hong, Song, Woon Ju, Rho, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269204/
https://www.ncbi.nlm.nih.gov/pubmed/34042468
http://dx.doi.org/10.1128/mSystems.00053-21