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Intermittent Hypoxia and Hypercapnia Alter Diurnal Rhythms of Luminal Gut Microbiome and Metabolome

Obstructive sleep apnea (OSA), characterized by intermittent hypoxia and hypercapnia (IHC), affects the composition of the gut microbiome and metabolome. The gut microbiome has diurnal oscillations that play a crucial role in regulating circadian and overall metabolic homeostasis. Thus, we hypothesi...

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Detalles Bibliográficos
Autores principales: Allaband, Celeste, Lingaraju, Amulya, Martino, Cameron, Russell, Baylee, Tripathi, Anupriya, Poulsen, Orit, Dantas Machado, Ana Carolina, Zhou, Dan, Xue, Jin, Elijah, Emmanuel, Malhotra, Atul, Dorrestein, Pieter C., Knight, Rob, Haddad, Gabriel G., Zarrinpar, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269208/
https://www.ncbi.nlm.nih.gov/pubmed/34184915
http://dx.doi.org/10.1128/mSystems.00116-21