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Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

The complex cell wall and biofilm matrix (ECM) act as key barriers to antibiotics in mycobacteria. Here, the ECM and envelope proteins of Mycobacterium marinum ATCC 927, a nontuberculous mycobacterial model, were monitored over 3 months by label-free proteomics and compared with cell surface protein...

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Detalles Bibliográficos
Autores principales: Savijoki, Kirsi, Myllymäki, Henna, Luukinen, Hanna, Paulamäki, Lauri, Vanha-aho, Leena-Maija, Svorjova, Aleksandra, Miettinen, Ilkka, Fallarero, Adyary, Ihalainen, Teemu O., Yli-Kauhaluoma, Jari, Nyman, Tuula A., Parikka, Mataleena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269238/
https://www.ncbi.nlm.nih.gov/pubmed/34156290
http://dx.doi.org/10.1128/mSystems.00500-21