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Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
The complex cell wall and biofilm matrix (ECM) act as key barriers to antibiotics in mycobacteria. Here, the ECM and envelope proteins of Mycobacterium marinum ATCC 927, a nontuberculous mycobacterial model, were monitored over 3 months by label-free proteomics and compared with cell surface protein...
Autores principales: | Savijoki, Kirsi, Myllymäki, Henna, Luukinen, Hanna, Paulamäki, Lauri, Vanha-aho, Leena-Maija, Svorjova, Aleksandra, Miettinen, Ilkka, Fallarero, Adyary, Ihalainen, Teemu O., Yli-Kauhaluoma, Jari, Nyman, Tuula A., Parikka, Mataleena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269238/ https://www.ncbi.nlm.nih.gov/pubmed/34156290 http://dx.doi.org/10.1128/mSystems.00500-21 |
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