Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N(2) in Dendritic Cells to Protect from Elevated Colitis

Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) plays a critical role in the pathogenesis of inflammatory bowel diseases (IBD). Mice lacking PTPN2 in dendritic cells (DCs) develop skin and liver inflammation by the age of 22 weeks due to a generalized loss of tolerance leading to uncontrolle...

Descripción completa

Detalles Bibliográficos
Autores principales: Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Niechcial, Anna, Riggs, Julianne B., Wawrzyniak, Marcin, Atrott, Kirstin, van de Sande, Marnix, Lang, Silvia, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269284/
https://www.ncbi.nlm.nih.gov/pubmed/34201918
http://dx.doi.org/10.3390/ijms22136820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269284/
https://www.ncbi.nlm.nih.gov/pubmed/34201918
http://dx.doi.org/10.3390/ijms22136820

Ejemplares similares