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Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma
The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance. In this study, we investigated a variety of therapeutic compounds in primary-derived uveal melanoma cell lines and fo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269285/ https://www.ncbi.nlm.nih.gov/pubmed/34201614 http://dx.doi.org/10.3390/ijms22136727 |