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Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma

The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance. In this study, we investigated a variety of therapeutic compounds in primary-derived uveal melanoma cell lines and fo...

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Detalles Bibliográficos
Autores principales:	Mergener, Svenja, Siveke, Jens T., Peña-Llopis, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269285/ https://www.ncbi.nlm.nih.gov/pubmed/34201614 http://dx.doi.org/10.3390/ijms22136727

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