OB-Folds and Genome Maintenance: Targeting Protein–DNA Interactions for Cancer Therapy

SIMPLE SUMMARY: Genome replication, repair, recombination, and the DNA damage response (DDR) rely on a cadre of DNA binding proteins to execute and regulate these critical pathways. There are many structural motifs that support DNA-binding and included in these is the oligonucleotide/oligosaccharide...

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Detalles Bibliográficos
Autores principales: Par, Sui, Vaides, Sofia, VanderVere-Carozza, Pamela S., Pawelczak, Katherine S., Stewart, Jason, Turchi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269290/
https://www.ncbi.nlm.nih.gov/pubmed/34283091
http://dx.doi.org/10.3390/cancers13133346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269290/
https://www.ncbi.nlm.nih.gov/pubmed/34283091
http://dx.doi.org/10.3390/cancers13133346

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