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Cohesin Mutations in Cancer: Emerging Therapeutic Targets

The cohesin complex is crucial for mediating sister chromatid cohesion and for hierarchal three-dimensional organization of the genome. Mutations in cohesin genes are present in a range of cancers. Extensive research over the last few years has shown that cohesin mutations are key events that contri...

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Detalles Bibliográficos
Autores principales: Antony, Jisha, Chin, Chue Vin, Horsfield, Julia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269296/
https://www.ncbi.nlm.nih.gov/pubmed/34202641
http://dx.doi.org/10.3390/ijms22136788