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Cohesin Mutations in Cancer: Emerging Therapeutic Targets
The cohesin complex is crucial for mediating sister chromatid cohesion and for hierarchal three-dimensional organization of the genome. Mutations in cohesin genes are present in a range of cancers. Extensive research over the last few years has shown that cohesin mutations are key events that contri...
Autores principales: | Antony, Jisha, Chin, Chue Vin, Horsfield, Julia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269296/ https://www.ncbi.nlm.nih.gov/pubmed/34202641 http://dx.doi.org/10.3390/ijms22136788 |
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