Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes

Mutations in splicing factors are recurrent somatic alterations identified in myelodysplastic syndromes (MDS) and they frequently coincide with mutations in epigenetic factors. About 25% of patients present concurrent mutations in such pathways, suggesting a cooperative role in the pathogenesis of M...

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Detalles Bibliográficos
Autores principales: Martínez-Valiente, Cristina, Garcia-Ruiz, Cristian, Rosón, Beatriz, Liquori, Alessandro, González-Romero, Elisa, Fernández-González, Raúl, Gómez-Redondo, Isabel, Cervera, José, Gutiérrez-Adán, Alfonso, Sanjuan-Pla, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269301/
https://www.ncbi.nlm.nih.gov/pubmed/34203454
http://dx.doi.org/10.3390/ijms22136963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269301/
https://www.ncbi.nlm.nih.gov/pubmed/34203454
http://dx.doi.org/10.3390/ijms22136963

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