Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort?

Chronic myeloid leukemia (CML) is a classical example of stem cell cancer since it arises in a multipotent hematopoietic stem cell upon the acquisition of the t(9;22) chromosomal translocation, that converts it into a leukemic stem cell (LSC). The resulting BCR-ABL1 fusion gene encodes a deregulated...

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Detalles Bibliográficos
Autores principales: Soverini, Simona, De Santis, Sara, Monaldi, Cecilia, Bruno, Samantha, Mancini, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269304/
https://www.ncbi.nlm.nih.gov/pubmed/34209376
http://dx.doi.org/10.3390/ijms22137093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269304/
https://www.ncbi.nlm.nih.gov/pubmed/34209376
http://dx.doi.org/10.3390/ijms22137093

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