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Alpha-Fetoprotein- and CD40Ligand-Expressing Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma

SIMPLE SUMMARY: In first clinical trials, vaccinations against tumor-associated antigens (TAA), such as Alpha-Fetoprotein (AFP) using antigen presenting cells, such as dendritic cells (DC), failed to achieve effective immune responses towards hepatocellular carcinoma (HCC). CD40Ligand is a potent im...

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Detalles Bibliográficos
Autores principales: Vogt, Annabelle, Sadeghlar, Farsaneh, Ayub, Tiyasha H., Schneider, Carlo, Möhring, Christian, Zhou, Taotao, Mahn, Robert, Bartels, Alexandra, Praktiknjo, Michael, Kornek, Miroslaw T., Toma, Marieta, Schmidt-Wolf, Ingo G. H., Branchi, Vittorio, Matthaei, Hanno, Kalff, Jörg C., Strassburg, Christian P., Gonzalez-Carmona, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269346/
https://www.ncbi.nlm.nih.gov/pubmed/34282787
http://dx.doi.org/10.3390/cancers13133375