Knocking out the Vitamin D Receptor Enhances Malignancy and Decreases Responsiveness to Vitamin D3 Hydroxyderivatives in Human Melanoma Cells

SIMPLE SUMMARY: Active forms of vitamin D3, including 1,25(OH)(2)D3, 20(OH)D3 and 1,20(OH)(2)D3, inhibited cell proliferation, migration rate and the ability to form colonies and spheroids in the wild-type melanoma cell line, while cells with the vitamin D receptor (VDR) silenced showed an increased...

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Detalles Bibliográficos
Autores principales: Podgorska, Ewa, Kim, Tae-Kang, Janjetovic, Zorica, Urbanska, Krystyna, Tuckey, Robert C., Bae, Sejong, Slominski, Andrzej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269360/
https://www.ncbi.nlm.nih.gov/pubmed/34206371
http://dx.doi.org/10.3390/cancers13133111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269360/
https://www.ncbi.nlm.nih.gov/pubmed/34206371
http://dx.doi.org/10.3390/cancers13133111

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