DNA G-Quadruplexes Contribute to CTCF Recruitment

G-quadruplex (G4) sites in the human genome frequently colocalize with CCCTC-binding factor (CTCF)-bound sites in CpG islands (CGIs). We aimed to clarify the role of G4s in CTCF positioning. Molecular modeling data suggested direct interactions, so we performed in vitro binding assays with quadruple...

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Detalles Bibliográficos
Autores principales: Tikhonova, Polina, Pavlova, Iulia, Isaakova, Ekaterina, Tsvetkov, Vladimir, Bogomazova, Alexandra, Vedekhina, Tatjana, Luzhin, Artem V., Sultanov, Rinat, Severov, Vjacheslav, Klimina, Ksenia, Kantidze, Omar L., Pozmogova, Galina, Lagarkova, Maria, Varizhuk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269367/
https://www.ncbi.nlm.nih.gov/pubmed/34209337
http://dx.doi.org/10.3390/ijms22137090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269367/
https://www.ncbi.nlm.nih.gov/pubmed/34209337
http://dx.doi.org/10.3390/ijms22137090

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