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Network Analysis Identifies Sex-Specific Gene Expression Changes in Blood of Amyotrophic Lateral Sclerosis Patients

Understanding the molecular mechanisms underlying the pathogenesis of amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, is a major challenge. We used co-expression networks implemented by the SWitch Miner software to identify switch genes associated with drastic transcrip...

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Detalles Bibliográficos
Autores principales: Santiago, Jose A., Quinn, James P., Potashkin, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269377/
https://www.ncbi.nlm.nih.gov/pubmed/34281203
http://dx.doi.org/10.3390/ijms22137150