The V-ATPase a3 Subunit: Structure, Function and Therapeutic Potential of an Essential Biomolecule in Osteoclastic Bone Resorption

This review focuses on one of the 16 proteins composing the V-ATPase complex responsible for resorbing bone: the a3 subunit. The rationale for focusing on this biomolecule is that mutations in this one protein account for over 50% of osteopetrosis cases, highlighting its critical role in bone physio...

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Detalles Bibliográficos
Autores principales: Chu, Anh, Zirngibl, Ralph A., Manolson, Morris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269383/
https://www.ncbi.nlm.nih.gov/pubmed/34203247
http://dx.doi.org/10.3390/ijms22136934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269383/
https://www.ncbi.nlm.nih.gov/pubmed/34203247
http://dx.doi.org/10.3390/ijms22136934

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