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Carfilzomib Promotes the Unfolded Protein Response and Apoptosis in Cetuximab-Resistant Colorectal Cancer

Cetuximab is a common treatment option for patients with wild-type K-Ras colorectal carcinoma. However, patients often display intrinsic resistance or acquire resistance to cetuximab following treatment. Here we generate two human CRC cells with acquired resistance to cetuximab that are derived from...

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Detalles Bibliográficos
Autores principales: Zulkifli, Ahmad, Tan, Fiona H., Areeb, Zammam, Stuart, Sarah F., Gomez, Juliana, Paradiso, Lucia, Luwor, Rodney B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269417/
https://www.ncbi.nlm.nih.gov/pubmed/34281166
http://dx.doi.org/10.3390/ijms22137114