Oxidized Alginate Dopamine Conjugate: In Vitro Characterization for Nose-to-Brain Delivery Application

Background: The blood–brain barrier (BBB) bypass of dopamine (DA) is still a challenge for supplying it to the neurons of Substantia Nigra mainly affected by Parkinson disease. DA prodrugs have been studied to cross the BBB, overcoming the limitations of DA hydrophilicity. Therefore, the aim of this...

Descripción completa

Detalles Bibliográficos
Autores principales: Trapani, Adriana, Corbo, Filomena, Agrimi, Gennaro, Ditaranto, Nicoletta, Cioffi, Nicola, Perna, Filippo, Quivelli, Andrea, Stefàno, Erika, Lunetti, Paola, Muscella, Antonella, Marsigliante, Santo, Cricenti, Antonio, Luce, Marco, Mormile, Cristina, Cataldo, Antonino, Bellucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269503/
https://www.ncbi.nlm.nih.gov/pubmed/34201634
http://dx.doi.org/10.3390/ma14133495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269503/
https://www.ncbi.nlm.nih.gov/pubmed/34201634
http://dx.doi.org/10.3390/ma14133495

Ejemplares similares