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Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

During development, homeostasis, and disease, organisms must balance responses that allow adaptation to low oxygen (hypoxia) with those that protect cells from oxidative stress. The evolutionarily conserved hypoxia-inducible factors are central to these processes, as they orchestrate transcriptional...

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Detalles Bibliográficos
Autores principales: Feng, Dingxia, Zhai, Zhiwei, Shao, Zhiyong, Zhang, Yi, Powell-Coffman, Jo Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270126/
https://www.ncbi.nlm.nih.gov/pubmed/34242227
http://dx.doi.org/10.1371/journal.pone.0249103