Cargando…

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

During development, homeostasis, and disease, organisms must balance responses that allow adaptation to low oxygen (hypoxia) with those that protect cells from oxidative stress. The evolutionarily conserved hypoxia-inducible factors are central to these processes, as they orchestrate transcriptional...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Dingxia, Zhai, Zhiwei, Shao, Zhiyong, Zhang, Yi, Powell-Coffman, Jo Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270126/ https://www.ncbi.nlm.nih.gov/pubmed/34242227 http://dx.doi.org/10.1371/journal.pone.0249103

Ejemplares similares

The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans
por: Zhang, Yi, et al.
Publicado: (2009)

HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans
por: Miller, Dana L., et al.
Publicado: (2011)

A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans
por: Papp, Diána, et al.
Publicado: (2012)

Whole genome profiling of short-term hypoxia induced genes and identification of HIF-1 binding sites provide insights into HIF-1 function in Caenorhabditis elegans
por: Feng, Dingxia, et al.
Publicado: (2023)

Temporal requirements of SKN-1/NRF as a regulator of lifespan and proteostasis in Caenorhabditis elegans
por: Grushko, Danielle, et al.
Publicado: (2021)

The Conserved SKN-1/Nrf2 Stress Response Pathway Regulates Synaptic Function in Caenorhabditis elegans
por: Staab, Trisha A., et al.
Publicado: (2013)

Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf
por: Ogawa, Takahiro, et al.
Publicado: (2016)

Catalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans
por: Seo, Hyun Won, et al.
Publicado: (2015)

Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans
por: Li, Hongyuan, et al.
Publicado: (2019)

skn-1 is required for interneuron sensory integration and foraging behavior in Caenorhabditis elegans
por: Wilson, Mark A., et al.
Publicado: (2017)

ICD-1/BTF3 antagonizes SKN-1-mediated endoderm specification in Caenorhabditis elegans
por: Ewe, Chee Kiang, et al.
Publicado: (2019)

Oleuropein Enhances Stress Resistance and Extends Lifespan via Insulin/IGF-1 and SKN-1/Nrf2 Signaling Pathway in Caenorhabditis elegans
por: Feng, Shiling, et al.
Publicado: (2021)

Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways
por: Jia, Wenjuan, et al.
Publicado: (2022)

O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans
por: Li, Hongyuan, et al.
Publicado: (2017)

SKN-1 Is a Negative Regulator of DAF-16 and Somatic Stress Resistance in Caenorhabditis elegans
por: Deng, Jianhui, et al.
Publicado: (2020)

Glucose negatively affects Nrf2/SKN-1-mediated innate immunity in C. elegans
por: Li, Le, et al.
Publicado: (2018)

The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans
por: Fontaine, Pauline, et al.
Publicado: (2018)

The activation of the oxidative stress response transcription factor SKN-1 in Caenorhabditis elegans by mitis group streptococci
por: Naji, Ali, et al.
Publicado: (2018)

PMK-1 p38 MAPK promotes cadmium stress resistance, the expression of SKN-1/Nrf and DAF-16 target genes, and protein biosynthesis in Caenorhabditis elegans
por: Keshet, Alex, et al.
Publicado: (2017)

East Indian sandalwood (Santalum album L.) oil confers neuroprotection and geroprotection in Caenorhabditis elegans via activating SKN-1/Nrf2 signaling pathway
por: Mohankumar, A., et al.
Publicado: (2018)

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1
por: Shao, Zhiyong, et al.
Publicado: (2010)

Selenite Enhances Immune Response against Pseudomonas aeruginosa PA14 via SKN-1 in Caenorhabditis elegans
por: Li, Wen-Hsuan, et al.
Publicado: (2014)

Onion Vinegar Quality Evaluation and its Alleviate Oxidative Stress Mechanism in Caenorhabditis elegans Via SKN-1
por: Wang, Jianfeng, et al.
Publicado: (2022)

Loss of muscleblind splicing factor shortens Caenorhabditis elegans lifespan by reducing the activity of p38 MAPK/PMK-1 and transcription factors ATF-7 and Nrf/SKN-1
por: Matilainen, Olli, et al.
Publicado: (2021)

Flavonol glycoside complanatoside A requires FOXO/DAF-16, NRF2/SKN-1, and HSF-1 to improve stress resistances and extend the life span of Caenorhabditis elegans
por: Tan, Lin, et al.
Publicado: (2022)

Chlorogenic Acid of Cirsium japonicum Resists Oxidative Stress Caused by Aging and Prolongs Healthspan via SKN-1/Nrf2 and DAF-16/FOXO in Caenorhabditis elegans
por: Cho, Myogyeong, et al.
Publicado: (2023)

MEKK-3 Acts Cooperatively with NSY-1 in SKN-1-Dependent Manner against Oxidative Stress and Aging in Caenorhabditis elegans
por: Hwang, Min, et al.
Publicado: (2022)

Octopamine-MAPK-SKN-1 signaling suppresses mating-induced oxidative stress in Caenorhabditis elegans gonads to protect fertility
por: Tsai, Yu, et al.
Publicado: (2023)

Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway
por: Dehghan, Esmaeil, et al.
Publicado: (2017)

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
por: Fang, Evandro F., et al.
Publicado: (2017)

The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK
por: Wu, Cheng-Wei, et al.
Publicado: (2016)

Selenocysteine mimics the effect of dietary restriction on lifespan via SKN-1 and retards age-associated pathophysiological changes in Caenorhabditis elegans
por: Kim, So-Hyeon, et al.
Publicado: (2018)

SKN-1/Nrf, A New Unfolded Protein Response Factor?
por: Choe, Keith P., et al.
Publicado: (2013)

Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans
por: Ackerman, Daniel, et al.
Publicado: (2012)

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage
por: Romney, Steven Joshua, et al.
Publicado: (2011)

Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans
por: Doering, Kelsie RS, et al.
Publicado: (2022)

Triclosan Disrupts SKN-1/Nrf2-Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells
por: Yoon, Dong Suk, et al.
Publicado: (2017)

Rosmarinus officinalis L. increases Caenorhabditis elegans stress resistance and longevity in a DAF-16, HSF-1 and SKN-1-dependent manner
por: Zamberlan, D.C., et al.
Publicado: (2016)

Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
por: Glover-Cutter, Kira M., et al.
Publicado: (2013)

Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
por: Steinbaugh, Michael J, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tce8vqldra8d0fa0pp94nqml1p