The Kras(G12D);Trp53(fl/fl) murine model of undifferentiated pleomorphic sarcoma is macrophage dense, lymphocyte poor, and resistant to immune checkpoint blockade

Sarcomas are rare, difficult to treat, mesenchymal lineage tumours that affect children and adults. Immunologically-based therapies have improved outcomes for numerous adult cancers, however, these therapeutic strategies have been minimally effective in sarcoma so far. Clinically relevant, immunolog...

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Detalles Bibliográficos
Autores principales: Hildebrand, Karys M., Singla, Arvind K., McNeil, Reid, Marritt, Kayla L., Hildebrand, Kurt N., Zemp, Franz, Rajwani, Jahanara, Itani, Doha, Bose, Pinaki, Mahoney, Douglas J., Jirik, Frank R., Monument, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270133/
https://www.ncbi.nlm.nih.gov/pubmed/34242269
http://dx.doi.org/10.1371/journal.pone.0253864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270133/
https://www.ncbi.nlm.nih.gov/pubmed/34242269
http://dx.doi.org/10.1371/journal.pone.0253864

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