Cargando…

The Kras(G12D);Trp53(fl/fl) murine model of undifferentiated pleomorphic sarcoma is macrophage dense, lymphocyte poor, and resistant to immune checkpoint blockade

Sarcomas are rare, difficult to treat, mesenchymal lineage tumours that affect children and adults. Immunologically-based therapies have improved outcomes for numerous adult cancers, however, these therapeutic strategies have been minimally effective in sarcoma so far. Clinically relevant, immunolog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hildebrand, Karys M., Singla, Arvind K., McNeil, Reid, Marritt, Kayla L., Hildebrand, Kurt N., Zemp, Franz, Rajwani, Jahanara, Itani, Doha, Bose, Pinaki, Mahoney, Douglas J., Jirik, Frank R., Monument, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270133/ https://www.ncbi.nlm.nih.gov/pubmed/34242269 http://dx.doi.org/10.1371/journal.pone.0253864

Ejemplares similares

A Trp53(fl/fl)Pten(fl/fl) mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging
por: Buchakjian, Marisa R., et al.
Publicado: (2017)

Intratumoral STING activation causes durable immunogenic tumor eradication in the KP soft tissue sarcoma model
por: Marritt, Kayla L., et al.
Publicado: (2023)

FL studio cookbook
por: Friedman, Shaun
Publicado: (2014)

Effect of cyclical intermittent hypoxia on Ad5CMVCre induced solitary lung cancer progression and spontaneous metastases in the Kras(G12D+); p53(fl/fl); myristolated p110(fl/fl) ROSA-gfp mouse
por: Guo, Xiaofeng, et al.
Publicado: (2019)

Chymase-Cre; Mcl-1(fl/fl) Mice Exhibit Reduced Numbers of Mucosal Mast Cells
por: Luo, Ying, et al.
Publicado: (2019)

Strangeness and heavy fl avours in Krakow
Publicado: (2011)

F.L. Shapiro: man and scientist
por: Joint Inst. Nucl. Res.
Publicado: (1998)

The DNA-recognition mode shared by archaeal feast/famine-regulatory proteins revealed by the DNA-binding specificities of TvFL3, FL10, FL11 and Ss-LrpB
por: Yokoyama, Katsushi, et al.
Publicado: (2009)

$f_L$ measurements in B → 𝑉𝑉decays at LHCb
por: Pereiro Castro, Asier
Publicado: (2021)

OpenFL: the open federated learning library
por: Foley, Patrick, et al.
Publicado: (2022)

Deletion of Mcpip1 in Mcpip1(fl/fl)Alb(Cre) mice recapitulates the phenotype of human primary biliary cholangitis
por: Kotlinowski, Jerzy, et al.
Publicado: (2021)

Le joueur de fl{circ}ute : poémes /
por: Perrier, Anne
Publicado: (1994)

Infants Fed a Lower Calorie Formula With 2′FL Show Growth and 2′FL Uptake Like Breast-Fed Infants
por: Marriage, Barbara J., et al.
Publicado: (2015)

Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 (iCre)Tbx21 (fl/fl) mice
por: Cuff, Antonia O., et al.
Publicado: (2017)

Mast cell‐deficient mice Mcpt5Cre/Dicer ( fl/fl ) redefine the role of mast cells in experimental bullous pemphigoid
por: Nsiah‐Dosu, S., et al.
Publicado: (2021)

RNA-Seq analysis of obese Pdha1(fl/fl)Lyz2-Cre mice induced by a high-fat diet
por: Geng, Zhaohong, et al.
Publicado: (2022)

Divertimento pour fl{circ}ute et piano
por: Françaix, Jean, 1912-1997
Publicado: (1955)

Dix-huit études pour fl{circ}ute /
por: Berbiguier, T. (Tranquille), 1782-1838
Publicado: (1957)

$f_L$ measurements with $B\to VV$ decays at LHCb
por: Pereiro Castro, Asier
Publicado: (2023)

Variability of banding patterns in chromosome Fl of the cat karyotype
por: Hageltorn, M
Publicado: (1977)

Calibration of Photonis XP3062/FL Photomultiplier Tube
por: Xiao, G
Publicado: (2005)

The Music Producer's Ultimate Guide to FL Studio 20
por: Au-Yeung, Joshua
Publicado: (2021)

Inhibitory Effect of Lactobacillus plantarum FL75 and Leuconostoc mesenteroides FL14 against Foodborne Pathogens in Artificially Contaminated Fermented Tomato Juices
por: Bah, Aïssé, et al.
Publicado: (2019)

Safety Aspect of Enterococcus faecium FL31 Strain and Antibacterial Mechanism of Its Hydroxylated Bacteriocin BacFL31 against Listeria monocytogenes
por: Chakchouk-Mtibaa, Ahlem, et al.
Publicado: (2018)

Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2′-FL Fucosyllactose (2′-FL) Human Milk Oligosaccharide
por: Ramirez-Farias, Carlett, et al.
Publicado: (2021)

Undifferentiated pleomorphic sarcoma
por: Premkumar, Jeyanthi, et al.
Publicado: (2012)

Undifferentiated pleomorphic sarcoma
por: de Paiva, Ana Carolina Gonçalves, et al.
Publicado: (2018)

The t(14;18) translocation is absent from endothelial and follicular dendritic cells of follicular lymphoma (FL) and shows heterogeneous presence in preserved FL mantle zones
por: Kosmidis, Perikles, et al.
Publicado: (2018)

Production of a p65(fl/fl)/LysMCre mouse model with dysfunctional NF-κB signaling in bone marrow-derived macrophages
por: Korkaya, Ahmet K., et al.
Publicado: (2023)

Topics in the geometry of projective space: recent work of FL Zak
por: Lazarsfeld, R, et al.
Publicado: (1984)

Correlation of Plasma FL Expression with Bone Marrow Irradiation Dose
por: Sproull, Mary, et al.
Publicado: (2013)

The LO-BaFL method and ALS microarray expression analysis
por: Baciu, Cristina, et al.
Publicado: (2012)

American Society of Hematology 2020 Podcast Collection: FL and DLBCL
por: Fox, Christopher Paul, et al.
Publicado: (2021)

Transformation of FL into DLBCL with a PMBL gene expression signature
por: Loveday, Tristan, et al.
Publicado: (2022)

PLDP-FL: Federated Learning with Personalized Local Differential Privacy
por: Shen, Xiaoying, et al.
Publicado: (2023)

Barriers and facilitators to health during prison reentry to Miami, FL
por: Mohammad, Sofia, et al.
Publicado: (2023)

Pleomorphic Undifferentiated Sarcoma of the Penis
por: Hayek, Omar Reda El, et al.
Publicado: (2008)

Undifferentiated Pleomorphic Sarcoma in Mandible
por: Kim, Chul-Hwan, et al.
Publicado: (2014)

Undifferentiated pleomorphic sarcoma of the mandible
por: Benites, Bernar Monteiro, et al.
Publicado: (2020)

Shower Simulations, Comparison of FlUKA, GEANT4 and EGS4
por: Fernandez-Hernando, J L, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_ap6dnudga7rvpkecp504od83oa