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SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells

Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related modifier (SUMO) to this kinase impacts on multiple cellular functions, such as pr...

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Detalles Bibliográficos
Autores principales: Francia, Marcos, Stortz, Martin, Echegaray, Camila Vazquez, Oses, Camila, Verneri, Paula, Petrone, María Victoria, Toro, Ayelen, Waisman, Ariel, Miriuka, Santiago, Cosentino, María Soledad, Levi, Valeria, Guberman, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270172/
https://www.ncbi.nlm.nih.gov/pubmed/34242346
http://dx.doi.org/10.1371/journal.pone.0254447