Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios

Based on epidemiologic and embryologic patterns, nonsyndromic orofacial clefts– the most common craniofacial birth defects in humans– are commonly categorized into cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP), which are traditionally considered to be etiologically distin...

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Detalles Bibliográficos
Autores principales: Ray, Debashree, Venkataraghavan, Sowmya, Zhang, Wanying, Leslie, Elizabeth J., Hetmanski, Jacqueline B., Weinberg, Seth M., Murray, Jeffrey C., Marazita, Mary L., Ruczinski, Ingo, Taub, Margaret A., Beaty, Terri H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270211/
https://www.ncbi.nlm.nih.gov/pubmed/34242216
http://dx.doi.org/10.1371/journal.pgen.1009584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270211/
https://www.ncbi.nlm.nih.gov/pubmed/34242216
http://dx.doi.org/10.1371/journal.pgen.1009584

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