An integrative network-based approach for drug target indication expansion

BACKGROUND: The identification of a target-indication pair is regarded as the first step in a traditional drug discovery and development process. Significant investment and attrition occur during discovery and development before a molecule is shown to be safe and efficacious for the selected indicat...

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Detalles Bibliográficos
Autores principales: Han, Yingnan, Wang, Clarence, Klinger, Katherine, Rajpal, Deepak K., Zhu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270215/
https://www.ncbi.nlm.nih.gov/pubmed/34242265
http://dx.doi.org/10.1371/journal.pone.0253614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270215/
https://www.ncbi.nlm.nih.gov/pubmed/34242265
http://dx.doi.org/10.1371/journal.pone.0253614

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