Search for Non-Protein Protease Inhibitors Constituted with an Indole and Acetylene Core

A possible inhibitor of proteases, which contains an indole core and an aromatic polar acetylene, was designed and synthesized. This indole derivative has a molecular architecture kindred to biologically relevant species and was obtained through five synthetic steps with an overall yield of 37% from...

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Detalles Bibliográficos
Autores principales: Almaraz-Girón, Marco A., Calderón-Jaimes, Ernesto, Carrillo, Adrián Sánchez, Díaz-Cervantes, Erik, Alonso, Edith Castañón, Islas-Jácome, Alejandro, Domínguez-Ortiz, Armando, Castañón-Alonso, Sandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270299/
https://www.ncbi.nlm.nih.gov/pubmed/34201422
http://dx.doi.org/10.3390/molecules26133817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270299/
https://www.ncbi.nlm.nih.gov/pubmed/34201422
http://dx.doi.org/10.3390/molecules26133817

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