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Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

Current therapeutic protocols for the treatment of HIV infection consist of the combination of diverse anti-retroviral drugs in order to reduce the selection of resistant mutants and to allow for the use of lower doses of each single agent to reduce toxicity. However, avoiding drugs interactions and...

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Detalles Bibliográficos
Autores principales: Meleddu, Rita, Corona, Angela, Distinto, Simona, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Secci, Daniela, Onali, Alessia, Sanna, Erica, Esposito, Francesca, Cirone, Italo, Ortuso, Francesco, Alcaro, Stefano, Tramontano, Enzo, Mátyus, Péter, Maccioni, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270338/
https://www.ncbi.nlm.nih.gov/pubmed/34201561
http://dx.doi.org/10.3390/molecules26133821