Proximity proteomics of endothelial Weibel-Palade bodies identifies novel regulator of von Willebrand factor secretion

Weibel-Palade bodies (WPB) are unique secretory organelles of endothelial cells that store factors regulating vascular hemostasis and local inflammation. Endothelial activation triggers rapid exocytosis of WPB, leading to the surface presentation of adhesion molecules relevant for leukocyte rolling...

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Detalles Bibliográficos
Autores principales: Holthenrich, Anna, Drexler, Hannes C.A., Chehab, Tarek, Naß, Johannes, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270391/
https://www.ncbi.nlm.nih.gov/pubmed/31262780
http://dx.doi.org/10.1182/blood.2019000786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270391/
https://www.ncbi.nlm.nih.gov/pubmed/31262780
http://dx.doi.org/10.1182/blood.2019000786

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