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Proximity proteomics of endothelial Weibel-Palade bodies identifies novel regulator of von Willebrand factor secretion
Weibel-Palade bodies (WPB) are unique secretory organelles of endothelial cells that store factors regulating vascular hemostasis and local inflammation. Endothelial activation triggers rapid exocytosis of WPB, leading to the surface presentation of adhesion molecules relevant for leukocyte rolling...
Autores principales: | Holthenrich, Anna, Drexler, Hannes C.A., Chehab, Tarek, Naß, Johannes, Gerke, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270391/ https://www.ncbi.nlm.nih.gov/pubmed/31262780 http://dx.doi.org/10.1182/blood.2019000786 |
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