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MHC class I H2-K(b) negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling

Proteins of the major histocompatibility complex class I (MHC I), predominantly known for antigen presentation in the immune system, have recently been shown to be necessary for developmental neural refinement and adult synaptic plasticity. However, their roles in nonneuronal cell populations in the...

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Detalles Bibliográficos
Autores principales: Lin, Karin, Bieri, Gregor, Gontier, Geraldine, Müller, Sören, Smith, Lucas K., Snethlage, Cedric E., White, Charles W., Maybury-Lewis, Sun Y., Villeda, Saul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270425/
https://www.ncbi.nlm.nih.gov/pubmed/34181639
http://dx.doi.org/10.1371/journal.pbio.3001311