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Partial restoration of immune response in Hepatitis C patients after viral clearance by direct-acting antiviral therapy

BACKGROUND & AIMS: HCV CD4+ and CD8+ specific T cells responses are functionally impaired during chronic hepatitis C infection. DAAs therapies eradicate HCV infection in more than 95% of treated patients. However, the impact of HCV elimination on immune responses remain controversial. Here, we a...

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Detalles Bibliográficos
Autores principales: Llorens-Revull, Meritxell, Costafreda, Maria Isabel, Rico, Angie, Guerrero-Murillo, Mercedes, Soria, Maria Eugenia, Píriz-Ruzo, Sofía, Vargas-Accarino, Elena, Gabriel-Medina, Pablo, Rodríguez-Frías, Francisco, Riveiro-Barciela, Mar, Perales, Celia, Quer, Josep, Sauleda, Silvia, Esteban, Juan Ignacio, Bes, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270431/
https://www.ncbi.nlm.nih.gov/pubmed/34242330
http://dx.doi.org/10.1371/journal.pone.0254243